Press Releases

Cerco Medical Collaborates with University of California Irvine
on Diabetes Therapy

 

San Francisco, CA – July 1, 2009 – Cerco Medical has reached agreement with the University of California to sponsor research on the company's proprietary thin sheet bioartificial pancreas to treat diabetes. The University's lead researcher is Jonathan R. T. Lakey, Associate Professor and Director of Research in the Department of Surgery at the Medical School on the Irvine Campus.

Cerco Medical has invented and patented a thin alginate sheet to protect transplanted islets without immune suppression drugs. The Islet Sheet responds to changing blood sugar levels with the release of insulin in real time, mimicking the normal function of pancreatic islets. The Islet Sheet consists of live, functional islets contained within an immunologically protective coating made from a hydrogel polymer called alginate derived from kelp.

Scott King, President of Cerco Medical, commented, "We are pleased to be doing this research in our home state, California. As we were searching for a nearby collaborator, we were very pleased when the Irvine Medical School hired Jon Lakey to spearhead their new effort in islet transplantation. We worked with Jonathan at Edmonton with very positive results and are happy to be working with him again."

Dr. Lakey commented, "Perhaps the greatest need in the field of islet transplantation is to make the metabolic benefits available to patients with type 1 diabetes without immune suppression. Based on my prior collaboration with Cerco Medical, I am familiar with the technology and the team involved in this therapy. I believe that this technology has great promise for advancing the field of islet transplantation and moving towards our goal of islet transplantation without chronic immunosuppresion."


April 21, 2009 – Lux Research, which provides strategic advice and on-going intelligence for emerging technologies, today published a report on Cerco Medical LLC. Their take on the Islet Sheet is that it is an unmatched 'intriguing alternative to immunosupressant regimen or microencapsulated islets' and that their clients should monitor progress for licensing opportunity.'

Scott King, President of Cerco Medical, commented "This is the first published report on Cerco Medical since we restarted research, and we are please to see that it is positive."

If you have a subscribtion you can view the complete report at Lux Research

 

CERCO MEDICAL BEGINS COLLABORATION
WITH LAKEY GROUP AT UNIVERSITY OF CALIFORNIA, IRVINE
LEADING RESEARCH CENTER TO TEST BIOARTIFICIAL PANCREAS

SAN FRANCISCO, CALIFORNIA (July 15, 2008) - Cerco Medical, a privately held research company, today announced the start of collaborative research with Professor Jonathan Lakey at the University of California, Irvine.

Dr. Lakey was recently appointed Professor and Director of Research in the Department of Surgery at the University of California, Irvine Medical Center. He is well known as a leader in transplantation of islets of Langerhans as a therapy for type 1 diabetes. He led the Human Islet Laboratory at the University of Alberta, Edmonton during the development of the Edmonton Protocol. The company and Prof. Lakey’s group have planned animal studies designed to demonstrate that the Islet Sheet can function for extended periods without immune suppression.

“Professor Lakey is credited with many of the top advances in islet transplantation. Cerco Medical is pleased to work with him on this promising therapy,” commented Scott R. King, President of Cerco Medical. “We hope to make islet transplantation available to millions more people.”

Dr. Lakey commented, “I have a long history of working with the Cercomed team. I am pleased to expand, and further develop in vitro and in vivo studies to lead to the pivotal clinical trials.”

Cerco Medical’s proprietary Islet Sheet contains islets of Langerhans protected by a polymer coating which eliminates the need for the immune-suppressing drugs used in the Edmonton Protocol. The Islet Sheet can be retrieved at any time providing a measure of safety unavailable with other technologies. The Company believes that the transplantation of Islet Sheet encapsulated islets will become the treatment of choice for restoring insulin-dependent diabetics to normal health.

Type 1 diabetes is a chronic, debilitating autoimmune disease resulting in loss of islets. It is the leading cause of kidney failure, adult blindness and non-traumatic amputations and reduces life expectancy by 15 years and is enormously costly to the health care system.

The funding for this research is coming from the Hanuman Medical Foundation.


Cerco Medical announces the granting of European Patents on its proprietary encapsulation technology

 

San Francisco, CA – September 23, 2004 – Cerco Medical announced today that it has received notice that the European Patent Office intends to grant its European patent application for the fabrication and use of alginate in medical devices.  This grant when taken together with Cerco Medical’s previously issued US. Patent Number 6,125,225 provide the company with a very strong Intellectual Property position for its first product, the Islet Sheet, as well as other new medical product opportunities as they arise.

“This grant is very important to the company, reflecting significant advances in our core technology.  Such advances in thin sheet fabrication were previously thought not possible. Through our efforts they are now routine, easily reproduced, and form the foundation of our first product, the Islet Sheet,” remarked Scott R. King, President and Chief Executive Officer.  “Coupled with certain trade secrets, we are highly confident that we will be able to maintain a defined competitive advantage in any markets we wish to compete in either as Cerco Medical or through any prospective partners.”

Cerco Medical is in the preclinical stage of developing its proprietary encapsulation technology to be initially applied to type 1 diabetes.  Type 1 diabetes is a disease in which the human body’s ability to produce insulin has been arrested due to an autoimmune disorder.  Individuals with type 1 diabetes are currently faced with multiple daily insulin injections as well as frequent monitoring of blood sugar levels for the remainder of their lives.

Islet transplantation into individuals with type 1 diabetes to eliminate the need for insulin injections is now a proven medical protocol due to the pioneering efforts of Dr. James Shapiro and Dr. Jonathan R.T. Lakey at the University of Alberta at Edmonton.  Over 330 patients worldwide have received islet transplants under the Edmonton Protocol.

The Edmonton Protocol is limited by the requirement for toxic immune suppression drugs.  Application of Cerco Medical’s proprietary and patented technology is designed to eliminate the need for immune suppression and enable the Edmonton Protocol to be extended to a larger number of individuals with type 1 diabetes.

The company will shortly have European patents in all countries required to defend our major markets.