RANDY DORIAN


Hanuman Medical
PlasmaSeal L.L.C.
Cerco Medical, L.L.C.
2180 Palou Ave.
San Francisco, CA 94124

(415) 902-1201








Positions and Employment


1998-pres.    Executive V.P., Hanuman Medical  LLC
1996-pres.    Chief Science Officer, Cerco Medical LLC
1993-pres.    Senior V.P., PlasmaSeal LLC
1999-pres     Director, Truffles International LLC
2001-2007    Director, Sperm Analytics LLC
1991-1993    Sr. Scientist & Director, Process Devel, Transtech Medical, Inc.
1990-1991     Research Director, Trigenesis
1987-1992.    V.P., R&D and Director, California Truffle Co, Inc.
1985-1987      Director of Research and Development, BabaGene, Inc.
1981-1985      Senior Scientist, BioResponse, Inc.
1983-1985      Scientific Consultant, University of California at San Francisco
1982-1983      Scientific Consultant, University of California at San Diego
1979-1981      Research Associate, University of California at San Diego
1977-1979      Research Associate, Salk Institute for Biological Studies
1975-1976      Consultant in Mathematics, Rand Corporation
1973-1977      Research Technician, University of California at San Diego
1971-1972      Student Research Fellow, Scripps Institute of Oceanography
1970-1971      Army Scholar, Salk Institute for Biological Studies

Education and Honors

B.S., Biochemistry, 1975, Revelle College, University of California at San Diego
Honorary Doctorate in Aerospace Medicology (AMD), 1971, USAF Systems Command, Aerospace Medical Division

Publications

  • Dorian R., Bernheim, J. and Mendelsohn, J. Quantification of Entry into and Exit From the Cell Cycle in Phytohemagglutinin Stimulated Human Lymphocyte Cultures. Cell Tis. Kinet. 1973, 11, 33.
  • Bernheim, J., Dorian, R. and Mendelsohn, J. DNA Synthesis and Cell Proliferation in Stimulated Human Lymphocyte Cultures: Kinetics of Response to Phytohemagglutinin. J. Exptl. Med. 1973, 120 955.
  • Bernheim J., Dorian R., Djobadza M. and Mendelsohn, J. Lymphocyte PHA and PPA Stimulation as an In Vitro model for Recruitment: Proliferation Kinetics of the System. Cancer Treatment Reports, 1976, 1986.
  • Bernheim J., Dorian, R., Kelley, M. and Mendelsohn, J. Kinetics of DNA Synthesis, Cell Proliferation and Cell Death in Human Lymphocyte Stimulation by Phytohemagglutinin (PHA). Fed. Proc. 1976, 35, 821.
  • Bernheim J., Dorian, R. and Mendelsohn, J. "Pitfalls in the Lymphocyte Proliferation Assay: Variations in Proliferation Kinetics and Cold Thymidine Pools." Proc. 11th Leukocyte Culture Conf., Academic Press, 1977, 464.
  • Mendelsohn, J., Dorian, R., Castagnola, J. and Bernheim, J. "Is There Gene Amplification or Other Non-Duplicative DNA Synthesis in Phytohemagglutinin Stimulated Human Lymphocyte Cultures?" Proc. 11th Leukocyte Conf. Academic Press, 1977, 467.
  • Dorian, R., Mendelsohn, J. and Bernheim, J. Quantification of Entry Into and Exit From the Cell Cycle; An Analytical Method Without Pharmacological Perturbation. Scand. J. Immunol. 1977, 464.
  • Bernheim, J., Mendelsohn, J., Kelley, J. and Dorian, R. Kinetics of Death and Disintegration in Human Lymphocyte Cultures. Proc. Natl. Acad. Sci. 1977, 74, 2356.
  • Bernheim J., Dorian, R. and Mendelsohn, J. Kinetics of Lymphocyte Response to PHA and PPD Effects on Cell Density and Balance of DNA Synthesis and Mitosis. Scand. J. Immunol. 1977, 6, 681.
  • Fahey, R., Newton, G., Dorian R. and Kosower E. Analysis of Biological Thiols: Derivatization with Monobromotrimethylammoniobimane and Characterization by Electrophoresis and Chromatography. Anal. Biochem. 1980, 107, 1.
  • Fahey, R., Newton, G. Dorian, R. and Kosower, E. Analysis of Biological Thiols: Quantitative Determination of Thiols at the Picomole Level Based Upon Derivatization with Monobromobimane and Separation by Cation-Exchange Chromatography. Anal. Biochem. 1981, 111, 357.
  • Newton, G., Dorian, R. and Fahey, R. Analysis of Biological Thiols: Derivatization with Monobromobimanes and Separation by Reverse Phase High Performance Liquid Chromatography. Anal. Biochem. 1981, 114, 393.
  • Fahey, R., Dorian R. and Utley, I. New Methods for Analysis of WR2721, WR1065 and WR33278. Intl. J. Onc. Bio. Phys. 1981.
  • Cochrum, K., Jemtrud, S., and Dorian, R., Successful Xenografts in Mice with Microencapsulated Rat and Dog Islets. Transplant Proc, 1995 27, 3297-3301.
  • Storrs, R.W., Dorian, R., King, S., Lakey, J., and Rilo, H.. Preclinical Development of the Islet Sheet, Annals of the New York Academy of Sciences Vol. 944, October 2001.
  • King, S., Dorian, R. Storrs, R.W.,  Lakey, J. Requirements for Encapsulation Technology and the Challenges for Transplantation of Islets of Langerhans, Graft Vol. 4(7), pp. 491-9, Oct/Nov 2001.

Patents

US Patent 5429821; Non-fibrogenic high mannuronate alginate coated transplants, processes for their manufacture, and methods for their use. Dorian, Randel E., Cochrum, Kent C., Jemtrud, Susan A., 07/04/1995

US Patent 5434057; Sperm motility assay and devices. Dorian, Randel; 07/18/1995

US Patent 5521079; Microcapsule generating system containing an air knife and method of encapsulating. Dorian, Randel E., Cochrum, Kent C.; 05/28/1996

US Patent 5578314; Multiple layer alginate coatings of biological tissue for transplantation. Cochrum, Kent C., Dorian, Randel E., Jemtrud, Susan A.; 11/26/1996

US Patent 5585007; Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant. Antanavich, Richard D., Dorian, Randel; 12/17/1996

US Patent 5639467; Electrostatic process for manufacturing coated transplants and product. Dorian, Randel E., Cochrum, Kent C.; 06/17/1997

US Patent 5643594; Spin encapsulation apparatus and method of use. Dorian, Randel E., Cochrum, Kent C., Antanavich, Richard David; 07/01/1997

US Patent 5656468; Cells or tissue coated with non-fibrogenic alginate less than 200 μm thick. Dorian, Randel E., Cochrum, Kent C.; 08/12/1997US Patent 5693514; Non-fibrogenic high mannuronate alginate coated transplants, processes for their manufacture, and methods for their use. Dorian, Randel E., Cochrum, Kent C.; 12/02/1997

US Patent 5788662; Methods for making concentrated plasma and/or tissue sealant. Antanavich, Richard D., Dorian, Randel; 08/04/1998

US Patent 5814022; Method and apparatus for applying tissue sealant. Antanavich, Richard D.; Dorian, Randel; 09/29/1998

US Patent 5855613; Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change. Antanavich, Richard D., Dorian, Randel; 01/05/1999

US Patent 6063297; Method and apparatus for making concentrated plasma and/or tissue sealant. Antanavich, Richard D., Dorian, Randel; 05/16/2000

US Patent 6132396; Apparatus for applying tissue sealant. Antanavich, Richard D., Dorian, Randel; 10/17/2000

US Patent 6165225; Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change, processes for their manufacture, and methods for their use. Antanavich, Richard D., Dorian, Randel; 12/26/2000

US Patent 6214338; Plasma concentrate and method of processing blood for same. Antanavich, Richard D., Dorian, Randel; 04/10/2001

US Patent 6372244; Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change, processes for their manufacture, and methods for their use. Antanavich, Richard D., Dorian, Randel; 04/16/2002

US Patent 6905612; Plasma concentrate apparatus and method. Dorian, Randel, Storrs, Richard Wood; 06/14/2005

US Patent 7223346; Methods and apparatus for isolating platelets from blood. Dorian, Randel, King, Scott R., Storrs, Richard Wood; 05/29/2007

US Patent 7470371; Methods and apparatus for isolating platelets from blood. Dorian, Randel, King, Scott R., Storrs, Richard Wood; 12/30/2008

European Patent EP0642326; Non-fibrogenic, alginate-coated transplants, process of manufacture and method of use thereof. Dorian, Randel E., Cochrum, Kent C., Vreeland, Valerie; 09/05/2001

European Patent EP0765159; Spin encapsulation apparatus and method of use. Dorian, Randel E., Cochrum, Kent C., Antanavich, Richard David; 09/11/2002

European Patent EP0741550; Multiple layer alginate coatings of biological tissue for transplantation. Cochrum, Kent C., Dorian, Randel E., Jemtrud, Susan A.; 09/24/2003

Patent Applications

US Patent Application 20030205538; Methods and apparatus for isolating platelets from blood. Dorian, Randel, King, Scott R., Storrs, Richard W.; 11/06/2003

US Patent Application 20040182795; Apparatus and method for concentration of plasma from whole blood. Dorian, Randel, Storrs, Richard Wood; 09/23/2004

US Patent Application 20040182788; Plasma concentrate apparatus and method. Dorian, Randel, Storrs, Richard Wood; 09/23/2004

US Patent Application 20050186120; Methods and apparatus for isolating platelets from blood. Dorian, Randel, King, Scott R., Storrs, Richard Wood; 08/25/2005

US Patent Application 20050196874; Methods and apparatus for isolating platelets from blood. Dorian, Randel, King, Scott R., Storrs, Richard Wood; 09/08/2005

US Patent Application 20060175268; Plasma concentrator device. Dorian, Randel, Leach, Michael D., Storrs, Richard Wood; 08/10/2006

US Patent Application 20070034579. Methods and apparatus for isolating platelets from blood. Dorian, Randel, King, Scott R., Storrs, Richard Wood; 02/15/2007

US Patent Application 20080011684; Apparatus and method for preparation of platelet rich plasma and concentrates thereof. Dorian, Randel E., Leach, Michael D.; 01/17/2008

US Patent Application 20080283474; Buoy suspension fractionation system. Leach, Michael D., Dorian, Randel, Hoeppner, Jacy C.; 11/20/2008

US Patent Application 20090014391; Buoy Suspension Fractionation System. Leach, Michael D., Dorian, Randel, Hoeppner, Jacy C.; 01/15/2009

WIPO Patent Application WO/2003/092894; Method and apparatus for isolating platelets from blood. Dorian, Randel, Storrs, Richard Wood, King, Scott; 11/13/2003

WIPO Patent Application WO/2004/009207; Plasma concentrating apparatus and method. Dorian, Randel, Storrs, Richard Wood; 01/29/2004

WIPO Patent Application WO/2006/086199; Platelet rich plasma concentrate apparatus and method. Dorian, Randel, Leach, Michael D.; 08/17/2006

WIPO Patent Application WO/2006/086201; Platelet rich plasma concentrate apparatus and method. Dorian, Randel, Leach, Michael D.; 08/17/2006

WIPO Patent Application WO/2006/086200; Plasma concentrator device. Dorian, Randel, Leach, Michael D., Storrs, Richard Wood; 08/17/2006

WIPO Patent Application WO/2008/127639; Buoy suspension fractionation system. Leach, Michael D., Dorian, Randel, Hoeppner, Jacy C.; 10/23/2008